Juvelook vs fillers vs Sculptra vs Rejuran comparisons

Injectable skin treatments in Korea are no longer limited to traditional fillers. Today, patients can choose from collagen stimulators, skin boosters, and regenerative injectables, each designed for a different layer of the skin and a different aesthetic goal.

Among the most commonly compared options are Juvelook, dermal fillers, Sculptra, and Rejuran. While they are all injectables, they work in fundamentally different ways.

Understanding these differences is essential for achieving natural, long-term results.

What Is Juvelook?

Juvelook is a collagen-stimulating injectable that focuses on skin quality improvement rather than shape change.

It combines PDLLA (poly-D,L-lactic acid) with hyaluronic acid to provide:

• Immediate hydration
• Gradual collagen regeneration

Juvelook is injected into the upper to mid-dermis, where it spreads evenly.

Best for

• Improving skin texture and elasticity
• Refining pores
• Reducing fine lines
• Enhancing overall skin quality

What Juvelook does not do

• It does not create visible facial volume
• It does not reshape facial contours

Juvelook is often described as a skin-quality collagen booster.

What Are Dermal Fillers?

Dermal fillers are most commonly hyaluronic acid (HA)-based injectables designed to replace lost volume or reshape facial contours.

They work by physically occupying space in the tissue.

Best for

• Cheek, chin, and jawline contouring
• Nasolabial folds and marionette lines
• Lip augmentation
• Structural facial shaping

Characteristics

• Immediate, visible results
• Clear contour and projection
• Results are temporary but predictable

Limitations

• Do not improve overall skin quality
• Overuse can lead to stiffness or unnatural appearance

Fillers are shape-focused, not skin-regenerative.

What Is Sculptra?

Sculptra is a collagen biostimulator made from poly-L-lactic acid (PLLA).

Unlike fillers, Sculptra does not provide immediate volume. Instead, it stimulates the body to produce its own collagen over time.

Best for

• Generalized volume loss
• Facial thinning with aging
• Structural support rather than contour sculpting

Characteristics

• Gradual, long-term improvement
• Works over several months
• Results can last longer than HA fillers

Limitations

• Not ideal for precise contouring
• Requires proper dilution and technique
• Results are not immediate

Sculptra is often chosen for global facial rejuvenation.

What Is Rejuran?

Rejuran is a regenerative skin booster made from polynucleotides (PDRN), derived from salmon DNA.

Rejuran focuses on skin repair and healing, rather than volume or lifting.

Best for

• Damaged or sensitive skin
• Acne scars
• Fine lines
• Thinning or weakened skin barrier

Characteristics

• Improves skin resilience and hydration
• Enhances skin repair and regeneration
• Commonly used in under-eye and delicate areas

Limitations

• No volume or contour change
• Results are subtle and cumulative

Rejuran is considered a skin regeneration treatment, not a volumizer.

Key Differences in Treatment Focus

Primary Purpose

• Juvelook: Skin texture and collagen quality
• Fillers: Volume and shape
• Sculptra: Gradual collagen-based volume support
• Rejuran: Skin repair and regeneration

Injection Depth

• Juvelook: Upper to mid-dermis
• Fillers: Deep dermis or subdermal
• Sculptra: Deep dermis or subcutaneous layer
• Rejuran: Superficial dermis

Result Style

• Juvelook: Natural glow and refinement
• Fillers: Immediate structural change
• Sculptra: Progressive volume restoration
• Rejuran: Healthier, stronger skin over time

Can These Treatments Be Combined?

Yes. Korean clinics frequently combine these injectables to target different skin layers.

Common strategies include:

• Juvelook + Rejuran for texture and skin health
• Sculptra + Juvelook for structure and surface quality
• Fillers for contour, combined with Juvelook for skin refinement

The key is layered treatment planning, not choosing a single injectable.

How Korean Clinics Choose the Right Option

Korean dermatology emphasizes:

• Preserving facial softness
• Avoiding over-volumization
• Improving skin quality alongside structure

Rather than asking which injectable is “best,” clinics first determine:

• Whether the issue is texture, volume, or skin damage
• Which layer needs treatment
• How the face will age long-term

Which One Should You Choose?

Choose Juvelook if your concern is skin texture, pores, or elasticity.
Choose fillers if you want immediate contour or shape change.
Choose Sculptra if you need gradual, natural volume restoration.
Choose Rejuran if your skin needs repair, healing, or strengthening.

A proper consultation is essential, as choosing the wrong injectable often leads to disappointing results.

Final Thoughts

Juvelook, fillers, Sculptra, and Rejuran are not competitors, but tools designed for different purposes. The best outcomes in Korea come from understanding skin layers and combining treatments thoughtfully, rather than relying on a single solution.

Natural results come from correct indication, conservative dosing, and long-term planning.